Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13385106 | 0.87 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL28294103 | 0.81 | FFAR1 (0.61) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL2500159 | 0.81 | FFAR1 (0.61) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL31032827 | 0.79 | LMNA (0.64) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL96351 | 0.79 | LMNA (0.64) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL13209407 | 0.79 | LMNA (0.59) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL18969804 | 0.79 | LMNA (0.64) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL11415636 | 0.79 | LMNA (0.59) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL96350 | 0.79 | LMNA (0.59) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL18568523 | 0.79 | LMNA (0.59) | LMNAMAOAPTGS1CYP2D6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006053-A | Indoles useful for treating inflammation | BIOLIPOX AB (SE) | 2007-07-25 | — | — | CN | disclosed |
| EP-1140896-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000037455-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |