Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922100 | 0.90 | MAPT (0.44) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL7928471 | 0.88 | L3MBTL1 (0.46) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL7929438 | 0.86 | L3MBTL1 (0.47) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL23267299 | 0.84 | L3MBTL1 (0.55) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL7934226 | 0.82 | KDM4E (0.39) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL19456536 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL23267297 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL7931698 | 0.78 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL28173969 | 0.77 | LMNA (0.68) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL23268009 | 0.77 | CYP1A2 (0.48) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140896-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000037455-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |