Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928262 | 0.85 | TRPV4 (0.36) | TRPV4MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7928321 | 0.83 | HPGD (0.39) | TRPV4ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL523892 | 0.82 | TRPV4 (0.50) | TRPV4GRM5GPR35MEN1ALDH1A1 | |
| SCHEMBL7928398 | 0.80 | TRPV4 (0.49) | TRPV4GRM5GPR35MEN1ALDH1A1 | |
| SCHEMBL7930662 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAA | |
| SCHEMBL7927104 | 0.77 | AR (0.43) | GPR35ALDH1A1USP2KDM4EAR | |
| SCHEMBL1402437 | 0.76 | TRPV4 (0.61) | TRPV4GRM5MEN1ALDH1A1MAPT | |
| SCHEMBL5418640 | 0.74 | TRPV4 (0.59) | TRPV4GRM5ALDH1A1GABRG2GABRB3 | |
| SCHEMBL22140277 | 0.73 | TRPV4 (0.61) | TRPV4GRM5MEN1ALDH1A1MAPT | |
| SCHEMBL29710965 | 0.73 | TRPV4 (0.43) | TRPV4GRM5MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661350-B1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON CATALYTIC CHEM IND (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5817843-A | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5608091-A | SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0661350-A1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |