SCHEMBL7928461

SCHEMBL7928461

CCCCCCCCOc1c(Cl)c2c(c(Cl)c1Nc1ccc(C(=O)OCCCC)cc1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 6/20 0.46
HPGD P15428 2/20 0.44
RECQL P46063 1/20 0.44
MAPT P10636 4/20 0.43
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ESR1 P03372 2/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.43
NR1H2 P55055 1/20 0.43
RNASEL Q05823 1/20 0.43
PKM P14618 1/20 0.41
TP53 P04637 1/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928410 0.88 MAPT (0.47) STSHPGDRECQLMAPTRAB9A
SCHEMBL7930660 0.86 STS (0.47) STSHPGDRECQLMAPTRAB9A
SCHEMBL7928227 0.84 SMN1; SMN2 (0.48) HPGDMAPTRAB9ANPC1ALDH1A1
SCHEMBL7933149 0.83 CDC25B (0.37) HPGDALDH1A1
SCHEMBL7921420 0.82 CYP19A1 (0.41) MAPTALDH1A1SMN1; SMN2LMNACYP1A2
SCHEMBL7921400 0.81 HPGD (0.52) STSHPGDRECQLMAPTRAB9A
SCHEMBL7929952 0.80 MAPT (0.49) STSHPGDRECQLMAPTRAB9A
SCHEMBL7921187 0.79 MAPT (0.48) STSHPGDRECQLMAPTRAB9A
SCHEMBL7930639 0.79 HPGD (0.50) STSHPGDRECQLMAPTRAB9A
SCHEMBL7929778 0.78 MAPT (0.51) HPGDRECQLMAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed