SCHEMBL7933149

SCHEMBL7933149

CCCCCCCCOc1c(Cl)c2c(c(Cl)c1Nc1ccc(C#N)cc1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.37
UNG P13051 2/20 0.36
ADAMTS5 Q9UNA0 2/20 0.36
MGLL Q99685 1/20 0.36
PTGES O14684 3/20 0.35
ALOX5 P09917 3/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
TBXA2R P21731 2/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
KDM4E B2RXH2 2/20 0.34
HTT P42858 1/20 0.34
CXCR2 P25025 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SMPD1 P17405 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933074 0.85 TBXA2R (0.38) CDC25BUNGADAMTS5MGLLTBXA2R
SCHEMBL7921420 0.83 CYP19A1 (0.41) MGLLTBXA2RALDH1A1HTTCXCR2
SCHEMBL7928461 0.83 STS (0.46) ALDH1A1HPGD
SCHEMBL7930614 0.81 ADAMTS5 (0.40) ADAMTS5MGLLTBXA2RALDH1A1HPGD
SCHEMBL7927465 0.79 MGLL (0.40) ADAMTS5MGLLTBXA2RHPGDKDM4E
SCHEMBL7928410 0.76 MAPT (0.47) ALDH1A1HPGDKDM4EHTT
SCHEMBL7928227 0.76 SMN1; SMN2 (0.48) CDC25BALDH1A1HPGDKDM4E
SCHEMBL7930019 0.73 ADAMTS5 (0.46) CDC25BUNGADAMTS5
SCHEMBL7933295 0.70 ADAMTS5 (0.39) CDC25BADAMTS5SMPD1
SCHEMBL7933041 0.70 PDE4B (0.38) TBXA2RCXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed