Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876505 | 0.80 | ITGAL (0.40) | ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL28555563 | 0.76 | CA12 (0.44) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4244290 | 0.76 | MAPT (0.39) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1773322 | 0.73 | CMA1 (0.60) | CMA1GSK3AGSK3BALDH1A1MEN1 | |
| SCHEMBL20303778 | 0.72 | LMNA (0.57) | CMA1GSK3AGSK3BALDH1A1MEN1 | |
| SCHEMBL28865712 | 0.72 | ALDH1A1 (0.55) | CMA1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1126125 | 0.72 | GAA (0.50) | CMA1GSK3AGSK3BALDH1A1MEN1 | |
| SCHEMBL21496819 | 0.71 | KDM4E (0.42) | CMA1GSK3AGSK3BALDH1A1MAPT | |
| SCHEMBL31164198 | 0.71 | CMA1 (0.42) | CMA1GSK3AGSK3BALDH1A1MEN1 | |
| SCHEMBL7449650 | 0.71 | CMA1 (0.56) | CMA1GSK3AGSK3BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225463-B1 | REACTING S-AMINE COMPOUND WITH AN ALDEHYDE; REACTING WITH ACYL CHLORIDE IN PRESENCE OF TRIETHYLAMINE TO FORM DIASTEREOISOMERIC BETA-LACTAMS; SEPARATION; TREATING WITH CERIUM AMMONIUM NITRATE AND ACETONITRILE AND WATER | PHARMACHEMIE B.V. (NL) | 2001-05-01 | — | — | US | claimed |
| EP-0933360-A1 | Synthesis of new beta-lactams | PHARMACHEMIE B.V. (NL) | 1999-08-04 | — | — | EP | claimed |
| CN-1178906-C | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ���Ͽع�����˾ | 2004-12-08 | — | — | CN | disclosed |
| US-6225463-B1 | REACTING S-AMINE COMPOUND WITH AN ALDEHYDE; REACTING WITH ACYL CHLORIDE IN PRESENCE OF TRIETHYLAMINE TO FORM DIASTEREOISOMERIC BETA-LACTAMS; SEPARATION; TREATING WITH CERIUM AMMONIUM NITRATE AND ACETONITRILE AND WATER | PHARMACHEMIE B.V. (NL) | 2001-05-01 | — | — | US | disclosed |
| US-6225463-B1 | REACTING S-AMINE COMPOUND WITH AN ALDEHYDE; REACTING WITH ACYL CHLORIDE IN PRESENCE OF TRIETHYLAMINE TO FORM DIASTEREOISOMERIC BETA-LACTAMS; SEPARATION; TREATING WITH CERIUM AMMONIUM NITRATE AND ACETONITRILE AND WATER | PHARMACHEMIE B.V. (NL) | 2001-05-01 | — | — | US | disclosed |
| CN-1261876-A | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ABBOTT LAB (US) | 2000-08-02 | — | — | CN | disclosed |
| EP-0933360-A1 | Synthesis of new beta-lactams | PHARMACHEMIE B.V. (NL) | 1999-08-04 | — | — | EP | disclosed |
| EP-0933360-A1 | Synthesis of new beta-lactams | PHARMACHEMIE B.V. (NL) | 1999-08-04 | — | — | EP | disclosed |