Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928983 | 1.00 | ALOX15 (0.46) | ALOX15ALOX12CNR2SMN1; SMN2CYP24A1 | |
| SCHEMBL7940402 | 1.00 | ALOX15 (0.46) | ALOX15ALOX12CNR2SMN1; SMN2CYP24A1 | |
| SCHEMBL25533461 | 0.89 | ALOX15 (0.35) | ALOX15ALOX12CNR2SMN1; SMN2CYP24A1 | |
| SCHEMBL7937093 | 0.88 | ADRB2 (0.42) | ALOX15ALOX12SMN1; SMN2CYP24A1HTT | |
| SCHEMBL8431879 | 0.85 | SMN1; SMN2 (0.45) | ALOX15ALOX12CNR2SMN1; SMN2CYP24A1 | |
| SCHEMBL7938209 | 0.85 | HTT (0.39) | ALOX15ALOX12SMN1; SMN2CYP24A1HTT | |
| SCHEMBL7938203 | 0.85 | HTT (0.39) | ALOX15ALOX12SMN1; SMN2CYP24A1HTT | |
| SCHEMBL7940499 | 0.85 | HTT (0.39) | ALOX15ALOX12SMN1; SMN2CYP24A1HTT | |
| SCHEMBL8431894 | 0.84 | POLB (0.36) | ALOX15ALOX12SMN1; SMN2LMNAHTT | |
| SCHEMBL7938308 | 0.82 | ALOX15 (0.52) | ALOX15ALOX12SMN1; SMN2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248573-B1 | SULFONYLATING OR HALOGENATING A (S)-1-PHENYL-2-PROPANOL DERIVATIVE TO PRODUCE (S)-1-PHENYL-2-SUBSTITUTED PROPANE DERIVATIVE; CHEMICAL INTERMEDIATE FOR SYNTHESIS OF ANTIOBESITY DRUG | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0627397-B1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEM (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5508461-A | ANTIOBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0627397-A1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |