Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928983 | 0.89 | ALOX15 (0.46) | ALOX15ALOX12SMN1; SMN2CYP24A1CNR2 | |
| SCHEMBL7928980 | 0.89 | ALOX15 (0.46) | ALOX15ALOX12SMN1; SMN2CYP24A1CNR2 | |
| SCHEMBL7940402 | 0.89 | ALOX15 (0.46) | ALOX15ALOX12SMN1; SMN2CYP24A1CNR2 | |
| SCHEMBL7937093 | 0.87 | ADRB2 (0.42) | ALOX15ALOX12SMN1; SMN2CYP24A1HTT | |
| SCHEMBL25516130 | 0.86 | CNR2 (0.36) | ALOX15ALOX12SMN1; SMN2CYP24A1CNR2 | |
| SCHEMBL25516127 | 0.86 | CNR2 (0.36) | ALOX15ALOX12SMN1; SMN2CYP24A1CNR2 | |
| SCHEMBL25516141 | 0.86 | CNR2 (0.36) | ALOX15ALOX12SMN1; SMN2CYP24A1CNR2 | |
| SCHEMBL8431879 | 0.84 | SMN1; SMN2 (0.45) | ALOX15ALOX12SMN1; SMN2CYP24A1CNR2 | |
| SCHEMBL7938209 | 0.84 | HTT (0.39) | ALOX15ALOX12SMN1; SMN2CYP24A1HTT | |
| SCHEMBL7938203 | 0.84 | HTT (0.39) | ALOX15ALOX12SMN1; SMN2CYP24A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150966-A1 | ISOTOPICALLY ENRICHED 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE) AND STEREOISOMERS THEREOF | TERRAN BIOSCIENCES INC (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150966-A1 | ISOTOPICALLY ENRICHED 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE) AND STEREOISOMERS THEREOF | SLC6A3, DBH, PNMT | ALOX15 3744/4885ALOX12 3946/4885SMN1; SMN2 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.