SCHEMBL7929151

SCHEMBL7929151

N#Cc1ccc(-c2ccc(F)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.58
PTGS1 P23219 1/20 0.58
KIF11 P52732 3/20 0.58
KDM4E B2RXH2 1/20 0.57
TP53 P04637 1/20 0.57
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
PGR P06401 1/20 0.50
CYP11B2 P19099 3/20 0.49
CYP11B1 P15538 2/20 0.49
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CA1 P00915 1/20 0.48
GCGR P47871 2/20 0.46
MAPK14 Q16539 2/20 0.46
MAPK13 O15264 1/20 0.46
ALOX5 P09917 1/20 0.46
MAPK12 P53778 1/20 0.46
MAPK11 Q15759 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12444126 0.92
SCHEMBL39936 0.92
Water SCHEMBL28049243 0.92 KDM4E (0.64) MMP3PTGS1KIF11KDM4ETP53
Hydrochloric Acid SCHEMBL30942103 0.89 KDM4E (0.61) MMP3PTGS1KIF11KDM4ETP53
SCHEMBL7375936 0.89 KDM4E (0.61) MMP3PTGS1KIF11KDM4ETP53
SCHEMBL28783861 0.89 KDM4E (0.61) MMP3PTGS1KIF11KDM4ETP53
SCHEMBL28251780 0.89 KDM4E (0.61) MMP3PTGS1KIF11KDM4ETP53
Hydrogen Sulfide SCHEMBL9396299 0.89 TSHR (0.52) MMP3PTGS1KIF11KDM4ETP53
SCHEMBL23733812 0.87 PGR (0.50) MMP3PTGS1KIF11KDM4ETP53
SCHEMBL23733810 0.87 PGR (0.50) MMP3PTGS1KIF11KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022228449-A1 PREPARATION METHOD FOR POLYIMIDE RESIN AND THIN FILM THEREOF 上海瑞暨新材料科技有限公司 2022-11-03 WO claimed
CN-113201136-B Preparation method of polyimide resin and film thereof 上海瑞暨新材料科技有限公司 2022-01-07 CN claimed
CN-113201136-A Preparation method of polyimide resin and film thereof 上海瑞暨新材料科技有限公司 2021-08-03 CN claimed
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS EIKONIZO THERAPEUTICS, INC. (US) 2026-05-07 US disclosed
US-12370194-B2 Metalloenzyme inhibitor compounds EIKONIZO THERAPEUTICS, INC. (US) 2025-07-29 US disclosed
US-20240307391-A1 METALLOENZYME INHIBITOR COMPOUNDS EIKONIZO THERAPEUTICS, INC. (US) 2024-09-19 US disclosed
US-11938134-B2 Metalloenzyme inhibitor compounds EIKONIZO THERAPEUTICS, INC. (US) 2024-03-26 US disclosed
WO-2023167325-A1 IMMOBILIZED PALLADIUM CATALYST AND METHOD FOR PRODUCING SAME, AND APPLICATION OF THIS CATALYST TO COUPLING REACTION 国立研究開発法人理化学研究所 2023-09-07 WO disclosed
WO-2022228449-A1 PREPARATION METHOD FOR POLYIMIDE RESIN AND THIN FILM THEREOF 上海瑞暨新材料科技有限公司 2022-11-03 WO disclosed
US-20220088018-A1 METALLOENZYME INHIBITOR COMPOUNDS EIKONIZO THERAPEUTICS, INC. (US) 2022-03-24 US disclosed
CN-113201136-B Preparation method of polyimide resin and film thereof 上海瑞暨新材料科技有限公司 2022-01-07 CN disclosed
US-20120165343-A1 Glucagon Receptor Modulators PFIZER INC. (US) 2012-06-28 US disclosed
US-20120165343-A1 Glucagon Receptor Modulators PFIZER INC. (US) 2012-06-28 US disclosed
US-20120165343-A1 Glucagon Receptor Modulators PFIZER INC. (US) 2012-06-28 US disclosed
CN-101857517-A Method for preparing fluorobiaryl compound in pure water solution UNIV DALIAN TECH 2010-10-13 CN disclosed
US-7521581-B2 Catalyst composition and process for producing cross-coupled compound using same TOSOH CORPORATION (JP) 2009-04-21 US disclosed
US-7521581-B2 Catalyst composition and process for producing cross-coupled compound using same TOSOH CORPORATION (JP) 2009-04-21 US disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240307391-A1 METALLOENZYME INHIBITOR COMPOUNDS HDAC6, HDAC1, HDAC2 MMP3 74/4885PTGS1 2083/4885KIF11 1264/4885
US-20220088018-A1 METALLOENZYME INHIBITOR COMPOUNDS HDAC6, HDAC1, HDAC2 MMP3 74/4885PTGS1 2083/4885KIF11 1264/4885
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS HDAC6, HDAC3, HDAC1 MMP3 206/4885PTGS1 4313/4885KIF11 1009/4885
US-20120165343-A1 Glucagon Receptor Modulators GLP1R, GCGR, GPR119 MMP3 3485/4885PTGS1 706/4885KIF11 4048/4885
US-11938134-B2 Metalloenzyme inhibitor compounds HDAC6, HDAC1, HDAC2 MMP3 74/4885PTGS1 2083/4885KIF11 1264/4885
US-12370194-B2 Metalloenzyme inhibitor compounds HDAC6, HDAC1, HDAC2 MMP3 74/4885PTGS1 2083/4885KIF11 1264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.