SCHEMBL7929228

SCHEMBL7929228

CCCCCCc1ccc(-c2ccc3c(F)c(O)c(F)cc3c2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.41
ALOX5 P09917 3/20 0.41
CYP3A4 P08684 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RARB P10826 3/20 0.37
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7563652 0.85 ALOX5 (0.48) TYRALOX5CYP3A4MAPTMEN1
SCHEMBL7931978 0.82 ALOX5 (0.39) TYRALOX5CYP3A4MAPTMEN1
SCHEMBL7925805 0.81 RARB (0.54) CYP3A4MAPTMEN1TP53TSHR
SCHEMBL20093398 0.79 MGLL (0.48) TYRALOX5CYP3A4MAPTMEN1
SCHEMBL7557949 0.79 ALOX5 (0.54) TYRALOX5CYP3A4MAPTMEN1
SCHEMBL7926802 0.77 PTGS2 (0.46) CYP3A4TP53RARBKDM4EALDH1A1
SCHEMBL10617206 0.77 TYR (0.55) TYRALOX5CYP3A4MAPTMEN1
SCHEMBL6974032 0.77 TYR (0.55) TYRALOX5CYP3A4MAPTMEN1
SCHEMBL17108393 0.76 TYR (0.43) TYRALOX5CYP3A4MAPTMEN1
SCHEMBL7925860 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0946474-B1 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2001-11-07 EP disclosed
US-6159561-A FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICES HOECHST AKTIENGESELLSCHAFT (DE) 2000-12-12 US disclosed