⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344330 | 0.75 | CALM1 (0.50) | — | |
| SCHEMBL10269094 | 0.72 | TAAR1 (0.52) | — | |
| SCHEMBL28882809 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL8346985 | 0.72 | TRPA1 (0.43) | — | |
| Trimethylammonium SCHEMBL28358083 | 0.72 | TSHR (0.50) | — | |
| SCHEMBL13036680 | 0.72 | TDP1 (0.52) | — | |
| SCHEMBL21467451 | 0.71 | — | — | |
| SCHEMBL29066682 | 0.71 | — | — | |
| SCHEMBL22541636 | 0.71 | — | — | |
| SCHEMBL24685830 | 0.70 | TP53 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3075947-B1 | METHOD FOR MINING HYDROCARBONS FROM A SEDIMENTARY BASIN, BY MEANS OF A BASIN SIMULATION | IFP ENERGIES NOW (FR) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023017288-A1 | HEXAHYDRONAPHTHALEN-2-ONE DERIVATIVES FOR USE AGAINST A CORONAVIRUS INFECTION | TÁMOGATOTT KUTATÓCSOPORTOK IRODÁJA (HU) | 2023-02-16 | — | — | WO | disclosed |
| US-11318163-B2 | Combination immune therapy and cytokine control therapy for cancer treatment | ENLIVEX THERAPEUTICS LTD (IL) | 2022-05-03 | — | — | US | disclosed |
| US-11166031-B2 | Signaling of side information for inter prediction with geometric partitioning | BEIJING BYTEDANCE NETWORK TECHNOLOGY CO., LTD. (CN) | 2021-11-02 | — | — | US | disclosed |
| EP-3262028-B1 | N-(4-HYDROXY-4-METHYL-CYCLOHEXYL)-4-PHENYL-BENZENESULFONAMIDE AND N-(-4HYDROXY-4-METHYL-CYCLOHEXYL)-4-(2-PYRIDYL)-BENZENESULFONAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE | PIMCO 2664 LTD (GB) | 2021-10-27 | — | — | EP | disclosed |
| US-11122277-B2 | — | — | 2021-09-14 | — | — | US | disclosed |
| WO-2021046243-A2 | METHODS AND COMPOSITIONS FOR GENOMIC INTEGRATION | MYELOID THERAPEUTICS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |
| US-20210029372-A1 | SIGNALING OF SIDE INFORMATION FOR INTER PREDICTION WITH GEOMETRIC PARTITIONING | BYTEDANCE INC. | 2021-01-28 | — | — | US | disclosed |
| US-20200121718-A1 | COMBINATION IMMUNE THERAPY AND CYTOKINE CONTROL THERAPY FOR CANCER TREATMENT | ENLIVEX THERAPEUTICS LTD. (IL) | 2020-04-23 | — | — | US | disclosed |
| US-20190211466-A1 | SURFACE TREATED COPPER FOIL FOR HIGH SPEED PRINTED CIRCUIT BOARD PRODUCTS INCLUDING THE COPPER FOIL AND METHODS OF MAKING | CHANG CHUN PETROCHEMICAL CO., LTD. (TW) | 2019-07-11 | — | — | US | disclosed |
| EP-2201946-A1 | PAI-1 PRODUCTION INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2010-06-30 | — | — | EP | disclosed |
| WO-2010033626-A1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010027448-A1 | ISOTOPICALLY ENRICHED PYRIMIDIN-5-YL ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | ACTIMIS PHARMACEUTICALS INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| EP-1937639-B1 | PYRIDINAMINOSULFONYL SUBSTITUTED BENZAMIDES AS INHIBITORS OF CYTOCHROME P450 3A4 (CYP3A4) | PFIZER PROD INC (US) | 2010-03-03 | — | — | EP | disclosed |
| US-7649012-B2 | Compounds, pharmaceutical compositions containing same, and methods of use for same | FASGEN, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| WO-2009121872-A2 | TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2009-10-08 | — | — | WO | disclosed |
| EP-1749011-B1 | BICYCLIC HETEROCYCLES AS HIV INTEGRASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2008019090-A2 | AGONISTS OF THE SPHINGOSINE-1-PHOSPHATE RECEPTOR | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-02-14 | — | — | WO | disclosed |
| EP-1626976-B1 | OLEFIN POLYMERIZATION CATALYST SYSTEM | EXXONMOBIL CHEM PATENTS INC (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1626999-B1 | OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS | EXXONMOBIL CHEM PATENTS INC (US) | 2007-09-26 | — | — | EP | disclosed |