Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.38 |
| ▸ | RARG | P13631 | 11/20 | 0.38 |
| ▸ | RARA | P10276 | 8/20 | 0.38 |
| ▸ | RXRA | P19793 | 5/20 | 0.38 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929331 | 1.00 | RARB (0.38) | RARBRARGRARARXRARXRB | |
| SCHEMBL7931062 | 0.85 | RXRA (0.40) | RARBRARGRARARXRARXRB | |
| SCHEMBL9484150 | 0.80 | RXRA (0.42) | RARBRARGRARARXRARXRB | |
| SCHEMBL2223445 | 0.74 | RARB (0.53) | RARBRARGRARARXRARXRB | |
| SCHEMBL9483828 | 0.71 | RARB (0.63) | RARBRARGRARARXRARXRB | |
| SCHEMBL7922983 | 0.71 | RXRA (0.43) | RARBRARGRARARXRARXRB | |
| SCHEMBL10515704 | 0.71 | RARB (0.58) | RARBRARGRARARXRARXRB | |
| SCHEMBL10515701 | 0.71 | RARB (0.58) | RARBRARGRARARXRARXRB | |
| SCHEMBL7922809 | 0.67 | RXRA (0.43) | RARBRARGRARARXRARXRB | |
| SCHEMBL7931979 | 0.67 | RARB (0.36) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |