SCHEMBL7929469

SCHEMBL7929469

C=Cc1cccc(C(=O)c2ccccc2)c1C=C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.48
GAA P10253 2/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 3/20 0.43
ATM Q13315 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 2/20 0.41
AKT1 P31749 1/20 0.41
CDC25B P30305 1/20 0.40
HSP90AA1 P07900 1/20 0.39
PKM P14618 1/20 0.39
CCR6 P51684 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TLR9 Q9NR96 1/20 0.39
POLB P06746 1/20 0.39
NR4A1 P22736 1/20 0.39
CYP2C8 P10632 1/20 0.39
CYP2C9 P11712 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27466112 0.87 ALDH1A1 (0.35) GAAMAPTALDH1A1KMT2AAKT1
SCHEMBL7932920 0.86 MAPT (0.46) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL7932918 0.86 ALDH1A1 (0.36) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL31727764 0.85 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL173243 0.85 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL6693582 0.85 CES2 (0.47) AKR1C3MAPTATMAKT1NPSR1
SCHEMBL27536313 0.84 AKR1C3 (0.50) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL11027952 0.83 AKR1C3 (0.48) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL11176226 0.83 AKR1C3 (0.48) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL997602 0.82 ALDH1A1 (0.44) AKR1C3MAPTALDH1A1POLBNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101289565-B Polymethacrylimide foam/inorganic nano composite material and method for preparing same NAT UNIV DEFENSE TECHNOLOGY 2010-07-28 CN claimed
CN-101289565-A Polymethacrylimide foam/inorganic nano composite material and method for preparing same NAT UNIV DEFENSE TECHNOLOGY (CN) 2008-10-22 CN claimed
CN-101289565-B Polymethacrylimide foam/inorganic nano composite material and method for preparing same NAT UNIV DEFENSE TECHNOLOGY 2010-07-28 CN disclosed
CN-101289565-A Polymethacrylimide foam/inorganic nano composite material and method for preparing same NAT UNIV DEFENSE TECHNOLOGY (CN) 2008-10-22 CN disclosed
EP-1095005-A1 PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES ALBEMARLE CORPORATION (US) 2001-05-02 EP disclosed
EP-1063975-A1 CROSSLINKABLE MACROMERS BEARING INITIATOR GROUPS SurModics, Inc. (US) 2001-01-03 EP disclosed
US-6096920-A LARGE-SCALE PRODUCTION OF CERTAIN AROMATICALLY-SUBSTITUTED ALIPHATIC CARBOXYLIC ACIDS AND THEIR ACID DERIVATIVES ALBEMARLE CORPORATION (US) 2000-08-01 US disclosed
WO-2000002840-A1 PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES ALBEMARLE CORPORATION (US) 2000-01-20 WO disclosed
WO-1999047129-A1 CROSSLINKABLE MACROMERS BEARING INITIATOR GROUPS SURMODICS, INC. (US) 1999-09-23 WO disclosed
US-4065430-A Functional group containing polymer and method of preparing the same FUJI PHOTO FILM CO., LTD. (JA) 1977-12-27 US disclosed
US-3933885-A Cinnamylideneacetic acid esters FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed