SCHEMBL6693582

SCHEMBL6693582

C=Cc1cccc(C(=O)C(=O)c2ccccc2)c1C=C

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 13/20 0.47
CES1 P23141 12/20 0.47
AKT1 P31749 1/20 0.40
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP3A4 P08684 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.36
LMNA P02545 1/20 0.36
XBP1 P17861 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
NFE2L2 Q16236 1/20 0.35
AKR1C3 P42330 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065186 0.86 CES2 (0.54) CES2CES1AKT1MAPTSMN1; SMN2
SCHEMBL7929469 0.85 AKR1C3 (0.48) AKT1MAPTKDM4EATMNPSR1
Ammonia Solution, Strong SCHEMBL4936520 0.84 CES2 (0.52) CES2CES1AKT1MAPTSMN1; SMN2
Water SCHEMBL6094264 0.84 CES2 (0.52) CES2CES1AKT1MAPTSMN1; SMN2
SCHEMBL4936525 0.82 MAPT (0.47) CES2CES1AKT1MAPTKDM4E
SCHEMBL997602 0.80 ALDH1A1 (0.44) MAPTSMN1; SMN2KDM4EHPGDLMNA
Bicarbonate SCHEMBL10785635 0.80 ALDH1A1 (0.39) AKT1CYP2C19NFE2L2
Trimethylammonium SCHEMBL600110 0.79 RAB9A (0.46) CES2CES1AKT1MAPTSMN1; SMN2
Trimethylammonium SCHEMBL597991 0.79 RAB9A (0.46) CES2CES1AKT1MAPTSMN1; SMN2
Trimethylammonium SCHEMBL598821 0.79 RAB9A (0.46) CES2CES1AKT1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1429703-A2 ABSORBENT STRUCTURE ABSORBENT ARTICLE WATER ABSORBENT RESIN AND ITS PRODUCTION PROCESS AND EVALUATION METHOD Nippon Shokubai Co., Ltd. (JP) 2004-06-23 EP disclosed
US-20040019342-A1 Absorbent structure, absorbent article, water-absorbent resin, and its production process and evaluation method NIPPON SHOKUBAI CO., LTD. (JP) 2004-01-29 US disclosed
WO-2003026707-A2 ABSORBENT STRUCTURE, ABSORBENT ARTICLE, WATER-ABSORBENT RESIN, AND ITS PRODUCTION PROCESS AND EVALUATION METHOD NIPPON SHOKUBAI CO., LTD. (JP) 2003-04-03 WO disclosed