SCHEMBL27369224

SCHEMBL27369224

CCCOC(=O)C1C=CC=CC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
LMNA P02545 1/20 0.35
CHRM1 P11229 2/20 0.34
ESR1 P03372 1/20 0.34
TSHR P16473 1/20 0.34
SLC6A2 P23975 1/20 0.34
KDR P35968 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
DNTT P04053 1/20 0.33
PPP1CC P36873 1/20 0.33
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27393118 0.90 TSHR (0.39) ALDH1A1LMNAESR1TSHRTDP1
SCHEMBL27367444 0.86 NFKB1 (0.38) ALDH1A1TSHRKDM4ENFKB1NFKB2
SCHEMBL28843521 0.80 ALDH1A1 (0.33) ALDH1A1LMNACHRM1ESR1TSHR
SCHEMBL27496718 0.79 TSHR (0.38) ALDH1A1LMNACHRM1TSHRTDP1
SCHEMBL28116642 0.77 HCAR2 (0.43) ALDH1A1LMNACHRM1ESR1TSHR
SCHEMBL7929530 0.77 DNTT (0.37) ALDH1A1TSHRDNTTNFKB1NFKB2
SCHEMBL28776161 0.74 NFKB1 (0.39) NFKB1NFKB2RELA
SCHEMBL818264 0.73 ALDH1A1 (0.40) ALDH1A1LMNACHRM1ESR1TSHR
SCHEMBL27731593 0.73 NLRP3 (0.41) LMNADNTT
SCHEMBL27548114 0.72 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1197578-C Pharmaceutical suspension comprising nevirapine hemihydrate BOEHRINGER INGELHEIM PHARMA (US) 2005-04-20 CN claimed
CN-1268055-A Pharmaceutical suspension comprising nevirapine hemihydrate BOEHRINGER INGELHEIM PHARMA (US) 2000-09-27 CN claimed
CN-108135788-B Method for producing coating film 花王株式会社 2019-06-21 CN disclosed
CN-108135789-B Method for producing coating film 花王株式会社 2019-05-21 CN disclosed
CN-108135789-A METHOD FOR PRODUCING COATING FILM 花王株式会社 2018-06-08 CN disclosed
CN-108135788-A Method for producing coating film 花王株式会社 2018-06-08 CN disclosed
CN-104292229-A 2-phenoxy pyrimidinone analogues NEUROGEN CORP 2015-01-21 CN disclosed
CN-102215675-B Multipurpose ant bait BASF SE 2014-11-26 CN disclosed
CN-102271711-B Each of the immune reconstitution promoter or infection preventive agent for maintaining graft-versus-tumor effect ONO PHARMACEUTICAL CO 2014-06-18 CN disclosed
CN-102271711-A Each of the immune reconstitution promoter or infection preventive agent for maintaining graft-versus-tumor effect 2011-12-07 CN disclosed
CN-102215675-A Multipurpose ant bait BASF SE 2011-10-12 CN disclosed
CN-1197578-C Pharmaceutical suspension comprising nevirapine hemihydrate BOEHRINGER INGELHEIM PHARMA (US) 2005-04-20 CN disclosed
CN-1489576-A Cannabinod receptor ligands ���鹫˾ 2004-04-14 CN disclosed
CN-1388755-A deodorant composition KAO CORP (JP) 2003-01-01 CN disclosed
CN-1300215-A Preventives/remedies for skin diseases SHOWA DENKO KK (JP) 2001-06-20 CN disclosed
CN-1065428-C Matrix type patch preparations HISAMITSU PHARMACEUTICAL CO (JP) 2001-05-09 CN disclosed
CN-1277836-A Novel cleaning agent component with improved characteristics of sedimentation and hair conditioning properties JOHNSON & JOHNSON CONSUMER (US) 2000-12-27 CN disclosed
CN-1268055-A Pharmaceutical suspension comprising nevirapine hemihydrate BOEHRINGER INGELHEIM PHARMA (US) 2000-09-27 CN disclosed
CN-1171736-A Matrix type patch preparations HISAMITSU PHARMACEUTICAL CO (JP) 1998-01-28 CN disclosed
CN-87104230-A Different  oxazolidinone derivative and production method thereof 1987-12-23 CN disclosed