⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28916507 | 0.88 | NOS3 (0.39) | — | |
| SCHEMBL2075967 | 0.82 | NOS2 (0.47) | — | |
| SCHEMBL1767952 | 0.82 | HRH4 (0.41) | — | |
| SCHEMBL12449394 | 0.79 | NOS2 (0.50) | — | |
| SCHEMBL17226870 | 0.78 | — | — | |
| SCHEMBL2052342 | 0.77 | NOS2 (0.44) | — | |
| Hydrochloric Acid SCHEMBL17372329 | 0.76 | CA2 (0.40) | — | |
| SCHEMBL12844206 | 0.76 | — | — | |
| SCHEMBL4872734 | 0.76 | CYP1A2 (0.37) | — | |
| SCHEMBL793127 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100508745-C | A fencing | VESTERGAARD CO LTD (DK) | 2009-07-08 | — | — | CN | claimed |
| CN-1525815-A | A fencing | ֯ | 2004-09-01 | — | — | CN | claimed |
| US-20250243193-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | SYNGENE INTERNATIONAL LIMITED (IN) | 2025-07-31 | — | — | US | disclosed |
| CN-115697997-B | Substituted 3-phenoxyazetidin-1-yl-pyrazines having GPR52 agonistic activity | 勃林格殷格翰国际有限公司 | 2024-07-30 | — | — | CN | disclosed |
| EP-4126850-B1 | SUBSTITUTED 3-PHENOXYAZETIDIN-1-YL-PYRAZINES HAVING GPR52 AGONISTIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2024-04-17 | — | — | EP | disclosed |
| US-11780827-B2 | Substituted 3-phenoxyazetidin-1-yl-pyrazines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-11780827-B2 | Substituted 3-phenoxyazetidin-1-yl-pyrazines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-11780827-B2 | Substituted 3-phenoxyazetidin-1-yl-pyrazines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| EP-4126850-A1 | SUBSTITUTED 3-PHENOXYAZETIDIN-1-YL-PYRAZINES HAVING GPR52 AGONISTIC ACTIVITY | Boehringer Ingelheim International GmbH (DE) | 2023-02-08 | — | — | EP | disclosed |
| CN-115697997-A | Substituted 3-phenoxyazetidin-1-yl-pyrazines having GPR52 agonistic activity | 勃林格殷格翰国际有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20220356180-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL MYERS SQUIBB CO (US) | 2022-11-10 | — | — | US | disclosed |
| CN-1525815-A | A fencing | ֯ | 2004-09-01 | — | — | CN | disclosed |
| US-20040077875-A1 | (5-(((2,4,6-Trimethylphenyl)amino)carbonyl)-4-methyl-2 -thiazolyl)carbamic Acid, 1,1-dimethylethyl ester for example; treating immunological and oncological disorders such as inflammatory bowel disease or cancer | DAS JAGABANDHU (US) | 2004-04-22 | — | — | US | disclosed |
| US-20040073026-A1 | Autoimmune diseases; anticancer agents | DAS JAGABANDHU (US) | 2004-04-15 | — | — | US | disclosed |
| US-20040054186-A1 | Cyclic protein tyrosine kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-03-18 | — | — | US | disclosed |
| US-20040024208-A1 | Drugs such as (5-(((2,4,6-Trimethylphenyl)amino)carbonyl)-4-methyl-2-thiazolyl)carbamic acid, 1,1-dimethylethyl ester, used as enzyme inhibitors, for prohylaxis of inflammatory bowel disease; modulation of immunology | DAS JAGABANDHU (US) | 2004-02-05 | — | — | US | disclosed |
| US-6596746-B1 | protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders; dasatinib | BRISTOL-MYERS SQUIBB COMPANY | 2003-07-22 | — | — | US | disclosed |
| CN-1348370-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2002-05-08 | — | — | CN | disclosed |
| EP-1169038-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000062778-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB CO. (US) | 2000-10-26 | — | — | WO | disclosed |