Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1796140 | 0.88 | HTR7 (0.63) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL7922043 | 0.87 | HTR7 (0.58) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL2896629 | 0.85 | MAPT (0.63) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL23267299 | 0.84 | L3MBTL1 (0.55) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL10798879 | 0.84 | HTR7 (0.67) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL4185846 | 0.82 | HTR7 (0.61) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL11876204 | 0.81 | HTR7 (0.59) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL1305347 | 0.79 | HTR7 (0.58) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL10429651 | 0.79 | HTR7 (0.58) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL1590919 | 0.79 | HTR7 (0.58) | L3MBTL1MAPTKDM4ECYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140896-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000037455-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |