Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11876204 | 0.94 | HTR7 (0.59) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL10429651 | 0.92 | HTR7 (0.58) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL12704119 | 0.92 | HTR7 (0.58) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL4800847 | 0.92 | HTR7 (0.58) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL1590919 | 0.92 | HTR7 (0.58) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL1305347 | 0.92 | HTR7 (0.58) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL1796140 | 0.89 | HTR7 (0.63) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL2344935 | 0.87 | HTR7 (0.64) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL701534 | 0.87 | HTR7 (0.64) | HTR7CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL14038703 | 0.85 | CYP1A2 (0.53) | HTR7CYP1A2CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6287174-A | — | — | None | — | — | JP | disclosed |
| CN-107567433-B | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | 尤尼威蒂恩技术有限责任公司 | 2022-01-18 | — | — | CN | disclosed |
| EP-2484658-B1 | LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION USING SAME, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-20170305928-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC | 2017-10-26 | — | — | US | disclosed |
| US-9738658-B2 | Compounds as diacylglycerol acyltransferase inhibitors | GLAXOSMITHKLINE LLC (US) | 2017-08-22 | — | — | US | disclosed |
| WO-2017094872-A1 | ULTRAVIOLET ABSORBER | 国立大学法人大阪大学 | 2017-06-08 | — | — | WO | disclosed |
| US-20170081342-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC | 2017-03-23 | — | — | US | disclosed |
| US-20150336925-A1 | SUBSTITUTED BENZOFURAN, BENZOTHIOPHENE AND INDOLE MCL-1 INHIBITORS | VANDERBILT UNIVERSITY (US) | 2015-11-26 | — | — | US | disclosed |
| US-20150322082-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2015-11-12 | — | — | US | disclosed |
| US-9109157-B2 | Liquid crystal compound having negative dielectric anisotropy, liquid crystal composition and liquid crystal display device using the same | JNC CORPORATION (JP) | 2015-08-18 | — | — | US | disclosed |
| US-6492367-B1 | Sulfamato hydroxamic acid metalloprotease inhibitor | G. D. SEARLE & COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-6479709-B1 | Process for the production of styrene derivative | TOSOH CORPORATION (JP) | 2002-11-12 | — | — | US | disclosed |
| US-6472567-B2 | REACTING A GRIGNARD REAGENT PREPARED FROM A SUBSTITUTED PHENYL HALIDE, ESPECIALLY A TERT-BUTOXYPHENYL HALIDE, WITH A VINYL HALIDE IN THE PRESENCE OF A MANGANESE, IRON, COBALT OR RHODIUM CATALYST; PRODUCT FREE FROM BIPHENYL. | TOSOH CORPORATION (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6448250-B1 | INHIBITS THE ACTIVITY OF ONE OR MORE OF THE FOLLOWING MATRIX METALLOPROTEINASES: MMP-2, MMP-9, AND MMP-13, WHILE EXHIBITING SUBSTANTIALLY LESS INHIBITORY ACTIVITY AGAINST MMP-1 | G. D. SEARLE & COMPANY | 2002-09-10 | — | — | US | disclosed |
| CN-1362954-A | Sulfamidohydroxamic acid metalloprotease inhibitor | SEARLE & CO (US) | 2002-08-07 | — | — | CN | disclosed |
| US-20020026084-A1 | Process for the production of styrene compound, and styrene compound free from biphenyl | TOSOH CORPORATION (JP) | 2002-02-28 | — | — | US | disclosed |
| EP-1157021-A1 | SULFAMATO HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000046221-A1 | SULFAMATO HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-10 | — | — | WO | disclosed |
| JP-H06287174-A | NEW ONIUM SALT AND POSITIVE TYPE PHOTORESIST MATERIAL USING THE SAME | SHIN ETSU CHEM CO LTD | 1994-10-11 | — | — | JP | disclosed |
| WO-1992013820-A1 | PROCESS FOR THE PREPARATION OF ALKYL-4-HALOPHENYL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336925-A1 | SUBSTITUTED BENZOFURAN, BENZOTHIOPHENE AND INDOLE MCL-1 INHIBITORS | MCL1, BCL2L1, BCLAF1 | HTR7 2043/4885CYP1A2 2116/4885CYP2C9 3994/4885 |
| US-20170081342-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | DGAT1, DGAT2, LCAT | HTR7 3326/4885CYP1A2 847/4885CYP2C9 1039/4885 |
| US-20020026084-A1 | Process for the production of styrene compound, and styrene compound free from biphenyl | RNF4, GRHPR, SBDS | HTR7 1687/4885CYP1A2 91/4885CYP2C9 876/4885 |
| US-20170305928-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | DGAT1, DGAT2, DLAT | HTR7 4280/4885CYP1A2 2953/4885CYP2C9 3749/4885 |
| US-20150322082-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | DGAT1, DGAT2, LCAT | HTR7 3326/4885CYP1A2 847/4885CYP2C9 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.