Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28491907 | 0.86 | RAB9A (0.55) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL9121060 | 0.84 | L3MBTL1 (0.62) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL7193777 | 0.83 | NPC1 (0.51) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL7928075 | 0.81 | KMT2A (0.53) | RAB9ANPC1TDP1KMT2AMEN1 | |
| SCHEMBL30572 | 0.81 | TDP1 (0.77) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL28251466 | 0.81 | TDP1 (0.77) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL15524969 | 0.81 | TDP1 (0.77) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL12330301 | 0.80 | NPC1 (0.70) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL23367937 | 0.79 | RAB9A (0.61) | RAB9ANPC1TDP1CASP3SENP8 | |
| SCHEMBL7194988 | 0.79 | NPC1 (0.69) | RAB9ANPC1TDP1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |