Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7929758

CCCCCCC1=Cc2ccccc2C1[Zr+2](=C(c1ccccc1)c1ccccc1)C1C(CCCCCC)=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CYP2D6 P10635 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYSLTR2 Q9NS75 2/20 0.36
CYSLTR1 Q9Y271 2/20 0.36
CES2 O00748 2/20 0.34
CES1 P23141 2/20 0.34
NAAA Q02083 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
HTR2A P28223 1/20 0.32
PLK1 P53350 3/20 0.32
PLK3 Q9H4B4 3/20 0.32
KCNH2 Q12809 2/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7928132 0.95 LMNA (0.33) LMNACYP2D6CYP3A4CYP2C9TSHR
Hydrochloric Acid SCHEMBL7929746 0.86 CYP2D6 (0.41) LMNACYP2D6CYP3A4CYP2C9TSHR
Hydrochloric Acid SCHEMBL7929673 0.80 CYP2D6 (0.37) LMNACYP2D6CYP3A4CYP2C9TSHR
Hydrochloric Acid SCHEMBL3732679 0.78 CYP2D6 (0.36) LMNACYP2D6CYP3A4CYP2C9TSHR
Hydrochloric Acid SCHEMBL7932974 0.78 LMNA (0.32) LMNA
Hydrochloric Acid SCHEMBL3735374 0.78 CYP2D6 (0.34) LMNACYP2D6CYP3A4CYP2C9TSHR
Hydrochloric Acid SCHEMBL7927073 0.74 TDP1 (0.32) LMNACYP2D6CYP3A4CYP2C9TSHR
SCHEMBL29274353 0.74 CYP2D6 (0.43) LMNACYP2D6CYP3A4CYP2C9TSHR
Hydrochloric Acid SCHEMBL31024191 0.74 LMNA (0.39) LMNACES2CES1
Hydrochloric Acid SCHEMBL437861 0.74 LMNA (0.39) LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1153938-A1 CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-14 EP disclosed