SCHEMBL7929845

SCHEMBL7929845

CCc1ccc2c(c1)Cc1c-2ccc(CC)c1[Zr](Cl)Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920110 0.78 RAB9A (0.37) ALDH1A1RAB9ANPC1LMNAMAPT
Hydrochloric Acid SCHEMBL7929846 0.77 RAB9A (0.36) ALDH1A1RAB9ANPC1LMNAMAPT
SCHEMBL4894905 0.74 ALDH1A1 (0.46) ALDH1A1RAB9ANPC1LMNAMAPT
SCHEMBL3273190 0.67 METAP1 (0.39) ALDH1A1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL26778600 0.67 TSHR (0.43) ALDH1A1RAB9ANPC1LMNAMAPT
SCHEMBL5357579 0.66 ALDH1A1 (0.59) ALDH1A1RAB9ANPC1LMNAMAPT
SCHEMBL27318412 0.66 ALDH1A1 (0.48) ALDH1A1RAB9ANPC1LMNAMAPT
SCHEMBL23759836 0.65 METAP1 (0.43) ALDH1A1RAB9ANPC1LMNAMAPT
SCHEMBL10275726 0.65 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1LMNAMAPT
SCHEMBL27807317 0.65 ALDH1A1 (0.38) ALDH1A1RAB9ANPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709405-B1 Process for the production of olefin polymers TOSOH CORP (JP) 2001-05-02 EP disclosed