Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7929846 | 0.80 | RAB9A (0.36) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7605726 | 0.79 | PNMT (0.46) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL5351583 | 0.78 | PNMT (0.45) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7929845 | 0.78 | ALDH1A1 (0.34) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL4894905 | 0.77 | ALDH1A1 (0.46) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL3485944 | 0.72 | PNMT (0.49) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL29556841 | 0.72 | MPL (0.37) | RAB9ANPC1MAPTMAPK1HTR2A | |
| SCHEMBL28406754 | 0.72 | GABRA1 (0.34) | HTR2AHTR2CHTR2BGPR84PDK2 | |
| SCHEMBL8993336 | 0.71 | POLB (0.38) | ALDH1A1MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL30801339 | 0.71 | PNMT (0.41) | RAB9ANPC1ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | disclosed |