Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560984 | 0.84 | LMNA (0.51) | LMNATDP1PTGS2CES2CES1 | |
| SCHEMBL6272355 | 0.83 | LMNA (0.45) | LMNATDP1PTGS2CES2CES1 | |
| SCHEMBL9223222 | 0.79 | LMNA (0.42) | LMNATDP1PTGS2CES2CES1 | |
| SCHEMBL7052945 | 0.79 | LMNA (0.58) | LMNATDP1PTGS2CES2CES1 | |
| SCHEMBL11352148 | 0.78 | TDP1 (0.59) | LMNATDP1PTGS2CES2CES1 | |
| SCHEMBL16721070 | 0.76 | CES2 (0.56) | PTGS2CES2CES1ALDH1A1PDPK1 | |
| SCHEMBL16721069 | 0.76 | CES2 (0.56) | PTGS2CES2CES1ALDH1A1PDPK1 | |
| SCHEMBL16721072 | 0.76 | CES2 (0.56) | PTGS2CES2CES1ALDH1A1PDPK1 | |
| SCHEMBL9452454 | 0.75 | LMNA (0.53) | LMNATDP1PTGS2CES2CES1 | |
| SCHEMBL20534185 | 0.75 | ESR1 (0.57) | LMNATDP1PTGS2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001520284-A | — | — | 2001-10-30 | — | — | JP | claimed |
| EP-1023338-A1 | PREPARATION OF MULTIMODAL POLYMER COMPOSITIONS USING MULTINUCLEAR METALLOCENE CATALYSTS | SRI INTERNATIONAL (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999020665-A1 | PREPARATION OF MULTIMODAL POLYMER COMPOSITIONS USING MULTINUCLEAR METALLOCENE CATALYSTS | SRI INTERNATIONAL (US) | 1999-04-29 | — | — | WO | claimed |