Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.51 |
| ▸ | CES1 | P23141 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052945 | 0.98 | LMNA (0.58) | TDP1LMNACES2CES1MTNR1A | |
| SCHEMBL560984 | 0.93 | LMNA (0.51) | TDP1LMNACES2CES1MTNR1A | |
| SCHEMBL4614904 | 0.85 | MTNR1A (0.53) | TDP1LMNACES2CES1MTNR1A | |
| SCHEMBL4614326 | 0.85 | MTNR1A (0.53) | TDP1LMNACES2CES1MTNR1A | |
| SCHEMBL27526812 | 0.84 | CES2 (0.56) | TDP1LMNACES2CES1TBXAS1 | |
| SCHEMBL27608811 | 0.84 | CES2 (0.56) | TDP1LMNACES2CES1TBXAS1 | |
| SCHEMBL9312401 | 0.84 | CES2 (0.56) | TDP1LMNACES2CES1TBXAS1 | |
| SCHEMBL11896276 | 0.84 | CES2 (0.56) | TDP1LMNACES2CES1TBXAS1 | |
| SCHEMBL20534185 | 0.83 | ESR1 (0.57) | TDP1LMNACES2CES1MTNR1A | |
| SCHEMBL20534184 | 0.83 | ESR1 (0.57) | TDP1LMNACES2CES1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248998-A | COMPOUNDS USED AS PLASTICIZERS FOR POLYVINYL CHLORIDE; POLYMERS USED AS FIBERS, FILMS, MOLDED ARTICLES | STANDARD OIL COMPANY (INDIANA) (US) | 1981-02-03 | — | — | US | disclosed |