SCHEMBL7930203

SCHEMBL7930203

CCOC(OCC)[SiH](C)S

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8849265 0.75 THRB (0.44) THRBLMNA
SCHEMBL18787584 0.71 THRB (0.47) THRBLMNA
SCHEMBL27602653 0.71 THRB (0.40) THRBLMNA
SCHEMBL22406262 0.70 THRB (0.35) THRBLMNA
SCHEMBL15349124 0.67 THRB (0.36) THRBLMNA
SCHEMBL8849042 0.67 LMNA (0.47) THRBLMNA
SCHEMBL8511715 0.67 LMNA (0.47) THRBLMNA
SCHEMBL22116250 0.65 LMNA (0.39) THRBLMNA
SCHEMBL27783875 0.65 THRB (0.35) THRBLMNA
SCHEMBL8849404 0.65 LMNA (0.45) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232668-B Polyurethane-hot melt adhesive with low monomeric diisocyanate content and good crosslinking rate SIKA技术股份公司 2019-08-23 CN disclosed
CN-107779142-A Reactive polyolefin hotmelt with relatively low reactivating temperature and its purposes in vacuum deep-draw is laminated SIKA技术股份公司 2018-03-09 CN disclosed
CN-107075337-A Binding system with high response pretreating agent SIKA技术股份公司 2017-08-18 CN disclosed
CN-106232668-A There is low monomeric diisocyanate content and the polyurethane-hot melt adhesive of good crosslinking rate SIKA技术股份公司 2016-12-14 CN disclosed
CN-102036929-B Containing the adhesion promoter composition of aromatics secondary amino silanes SIKA TECHNOLOGY AG (CH) 2016-01-20 CN disclosed
CN-102666769-B Hot-melt adhesive composition with good adhesion not only to polar but also to non-polar substrates SIKA TECHNOLOGY AG 2015-06-03 CN disclosed
US-8865822-B2 Hot melt adhesive compositions having good adhesion on both polar and nonpolar substrates SIKA TECHNOLOGY AG (CH) 2014-10-21 US disclosed
CN-101573305-B Low temperature adhesive primer composition SIKA TECHNOLOGY AG 2013-03-13 CN disclosed
US-20120315491-A1 HOT MELT ADHESIVE COMPOSITIONS HAVING GOOD ADHESION ON BOTH POLAR AND NONPOLAR SUBSTRATES SIKA TECHNOLOGY AG (CH) 2012-12-13 US disclosed
CN-102666769-A Hot-melt adhesive composition with good adhesion not only to polar but also to non-polar substrates SIKA TECHNOLOGY AG 2012-09-12 CN disclosed
CN-101591466-B Adhesive compound containing epoxy resin SIKA TECHNOLOGY AG (CH) 2011-12-14 CN disclosed
CN-102036929-A Aromatic secondary adhesive compositions containing aminosilane SIKA TECHNOLOGY AG 2011-04-27 CN disclosed
CN-101591466-A The adhesion promoter composition that comprises Resins, epoxy SIKA TECHNOLOGY AG (CH) 2009-12-02 CN disclosed
CN-101573305-A Low temperature adhesive primer composition SIKA TECHNOLOGY AG (CH) 2009-11-04 CN disclosed
US-6177526-B1 METALLOCENE; COCATALYST; MODIFIED OXIDE CONTAINS ORGANIC SILICON RADICALS CONTAINING AT LEAST ONE OF THE GROUPS NITROGEN, FLUORINE, PHOSPHORUS OR SULFUR. TARGOR GMBH (DE) 2001-01-23 US disclosed