SCHEMBL7930428

SCHEMBL7930428

COC(=O)C(Cl)=Cc1cc(-n2c(OC)nc(C(F)(F)F)cc2=O)ccc1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 5/20 0.35
ALPI P09923 4/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
NOTUM Q6P988 1/20 0.32
KDM4E B2RXH2 2/20 0.32
PKM P14618 1/20 0.32
PTGS2 P35354 2/20 0.32
TP53 P04637 1/20 0.32
IGF1R P08069 1/20 0.32
CCR1 P32246 2/20 0.32
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PTGS1 P23219 1/20 0.31
MAT2A P31153 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930426 1.00 ALPL (0.35) ALPLALPIMEN1KMT2AALDH1A1
SCHEMBL7933742 0.80 ALDH1A1 (0.38) ALPLALPIMEN1KMT2AALDH1A1
SCHEMBL7933744 0.80 ALDH1A1 (0.38) ALPLALPIMEN1KMT2AALDH1A1
SCHEMBL9423037 0.79 KMT2A (0.38) ALPLALPIMEN1KMT2AALDH1A1
SCHEMBL10411515 0.79 TDP1 (0.48) ALPLMEN1KMT2AALDH1A1POLB
SCHEMBL7020529 0.74 NPBWR1 (0.37) ALDH1A1NOTUMKDM4ECCR1LMNA
SCHEMBL10410041 0.74 MEN1 (0.40) ALPLALPIMEN1KMT2AALDH1A1
SCHEMBL10533665 0.74 MEN1 (0.40) ALPLMEN1KMT2AALDH1A1PTGS2
SCHEMBL7963358 0.71 NOTUM (0.30) NOTUM
SCHEMBL7023491 0.71 NPBWR1 (0.38) KMT2AALDH1A1NOTUMCCR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031865-A1 Substituted 3-phenyluracils KLINTZ RALF (DE) 2001-10-18 US disclosed
US-6239074-B1 HERBICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031865-A1 Substituted 3-phenyluracils CCR1, CCR6, CCR3 ALPL 4858/4885ALPI 4616/4885MEN1 2721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.