Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 4/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.36 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934863 | 0.90 | DRD2 (0.46) | KCNH2FDFT1PTGDR2DRD2DRD4 | |
| SCHEMBL7931623 | 0.89 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL7934901 | 0.87 | MAOB (0.40) | KCNH2 | |
| SCHEMBL9804456 | 0.83 | FDFT1 (0.54) | FDFT1 | |
| SCHEMBL7932190 | 0.76 | APP (0.40) | KCNH2 | |
| SCHEMBL7932222 | 0.76 | DRD2 (0.43) | KCNH2DRD2DRD4DRD3 | |
| SCHEMBL7930475 | 0.75 | FDFT1 (0.52) | FDFT1 | |
| SCHEMBL7931627 | 0.74 | CETP (0.49) | FDFT1 | |
| SCHEMBL9804487 | 0.74 | CETP (0.49) | FDFT1 | |
| SCHEMBL7934874 | 0.73 | FDFT1 (0.53) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |