Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932190 | 0.88 | APP (0.40) | KCNH2APP | |
| SCHEMBL7932222 | 0.88 | DRD2 (0.43) | MAOBKCNH2APPPPARGPPARA | |
| SCHEMBL7930430 | 0.87 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL7931623 | 0.77 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL7934863 | 0.76 | DRD2 (0.46) | KCNH2PPARGPPARA | |
| SCHEMBL1620167 | 0.72 | APP (0.52) | MAOBAPP | |
| SCHEMBL7922572 | 0.72 | FDFT1 (0.41) | MAOB | |
| SCHEMBL9804456 | 0.71 | FDFT1 (0.54) | — | |
| SCHEMBL15079869 | 0.71 | MAOB (0.58) | MAOBAPPHRH3 | |
| SCHEMBL25703553 | 0.69 | HTR7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |