Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934901 | 0.88 | MAOB (0.40) | PPARGPPARAMAOBKCNH2APP | |
| SCHEMBL7932190 | 0.87 | APP (0.40) | KMT2AMEN1KCNH2APPSMN1; SMN2 | |
| SCHEMBL10981393 | 0.77 | DRD2 (0.56) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL7931623 | 0.76 | KCNH2 (0.41) | TDP1L3MBTL1KCNH2 | |
| SCHEMBL7930430 | 0.76 | KCNH2 (0.43) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL10980254 | 0.70 | APP (0.57) | DRD2DRD4DRD3MAOBKMT2A | |
| SCHEMBL9491970 | 0.69 | FDFT1 (0.50) | PPARGPPARA | |
| SCHEMBL10980719 | 0.69 | DRD4 (0.53) | DRD2DRD4DRD3MAOBKMT2A | |
| SCHEMBL11003782 | 0.68 | KMT2A (0.51) | PPARGPPARAMAOBKMT2AMEN1 | |
| SCHEMBL11003805 | 0.68 | LMNA (0.51) | PPARGPPARAMAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |