Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930472 | 0.85 | MAOB (0.41) | ALDH1A1MAPTMAOBMGLLFFAR1 | |
| SCHEMBL7922518 | 0.78 | NQO1 (0.48) | KMT2ASMN1; SMN2ALDH1A1MAPTUSP2 | |
| SCHEMBL6637857 | 0.76 | HTT (0.45) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8560939 | 0.76 | HTT (0.48) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL507033 | 0.76 | MAOB (0.50) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5384421 | 0.75 | HTT (0.50) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5382500 | 0.75 | APP (0.53) | HTTKMT2ASMN1; SMN2MAPTMAOB | |
| SCHEMBL29926061 | 0.75 | FFAR1 (0.54) | HTTKMT2ASMN1; SMN2FFAR1LMNA | |
| SCHEMBL7932196 | 0.73 | POLB (0.44) | ALDH1A1MAPTPOLBTDP1LMNA | |
| SCHEMBL6650023 | 0.73 | ALDH1A1 (0.57) | KMT2ASMN1; SMN2ALDH1A1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |