SCHEMBL7930485

SCHEMBL7930485

CCCc1cc(C#N)cc(CCC)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.40
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
TTR P02766 2/20 0.34
ALB P02768 2/20 0.34
CYP2A6 P11509 1/20 0.34
HSD17B10 Q99714 3/20 0.34
KDM4E B2RXH2 2/20 0.34
BCAT2 O15382 1/20 0.34
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 3/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
CYP19A1 P11511 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927098 0.88 TSHR (0.39) HRH4MAPK1RECQLMEN1KMT2A
SCHEMBL7928482 0.83 HTT (0.46) MEN1KMT2ATTRALBCYP2A6
SCHEMBL24017194 0.81 MEN1 (0.37) HRH4MEN1KMT2ATTRALB
SCHEMBL3678133 0.80 GABRA1 (0.42) HRH4MEN1KMT2ATTRALB
SCHEMBL7930484 0.79 MEN1 (0.36) HRH4MEN1KMT2ATTRALB
SCHEMBL20526615 0.79 HRH4 (0.46) HRH4MEN1KMT2ACYP2A6HSD17B10
SCHEMBL9326441 0.75 ALDH1A1 (0.38) TSHRMAPTGAAALDH1A1HTT
SCHEMBL19175665 0.75 HRH4 (0.46) HRH4MEN1KMT2ACYP2A6HSD17B10
SCHEMBL7927295 0.73 TTR (0.33) HRH4MEN1KMT2ATTRALB
SCHEMBL6131303 0.73 GABRA1 (0.37) MAPTALDH1A1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed