Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174991 | 0.83 | TLR8 (0.43) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| Methane SCHEMBL16027128 | 0.83 | TLR8 (0.41) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL6131303 | 0.82 | GABRA1 (0.37) | ALDH1A1CYP3A4ALOX5HTTPOLB | |
| SCHEMBL20788166 | 0.82 | NOS2 (0.47) | ALDH1A1TSHRHTTPOLBNOS3 | |
| SCHEMBL31614612 | 0.82 | DHFR (0.35) | ALDH1A1HTTPOLBGABRA1GABRB2 | |
| SCHEMBL1100124 | 0.80 | DHFR (0.41) | HTTPOLBNOS3NOS1NOS2 | |
| SCHEMBL20681193 | 0.80 | HMGCR (0.41) | TP53HTTPOLBGABRA1GABRB2 | |
| SCHEMBL5381343 | 0.78 | HTT (0.34) | ALDH1A1HTTPOLBNOS3NOS1 | |
| SCHEMBL3940715 | 0.78 | HMGCR (0.35) | ALDH1A1HTTPOLBNOS3NOS1 | |
| SCHEMBL2186186 | 0.78 | HTT (0.54) | ALDH1A1TP53CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407172-B1 | Aromatic polyimide separation membrane | MITSUBISHI CHEM IND (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-5112941-A | A fluorinated membranes with high selectivity | MITSUBISHI KASEI CORPORATION (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0437611-A1 | SEPARATIVE MEMBRANE MADE OF AROMATIC POLYIMIDE | MITSUBISHI KASEI CORPORATION (JP) | 1991-07-24 | — | — | EP | disclosed |
| EP-0407172-A1 | Aromatic polyimide separation membrane | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-09 | — | — | EP | disclosed |