SCHEMBL7930599

SCHEMBL7930599

CCCCOc1c(F)c2c(c(F)c1Nc1c(F)c(F)cc(F)c1F)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MCL1 Q07820 1/20 0.35
POLH Q9Y253 1/20 0.35
ELANE P08246 3/20 0.34
STK17B O94768 1/20 0.33
FAAH O00519 3/20 0.32
CCNB2 O95067 1/20 0.32
CCNE2 O96020 1/20 0.32
CDK1 P06493 1/20 0.32
CDK4 P11802 1/20 0.32
CCNB1 P14635 1/20 0.32
CCND1 P24385 1/20 0.32
CCNE1 P24864 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921560 0.95 SMPD1 (0.37) ELANECTSG
SCHEMBL7930633 0.85 ELANE (0.38) MEN1NPC1ALDH1A1GAAMAPT
SCHEMBL7930686 0.85 ELANE (0.38) MEN1NPC1ALDH1A1GAAMAPT
SCHEMBL7928355 0.84 ELANE (0.37) MEN1NPC1ALDH1A1GAAMAPT
SCHEMBL7930657 0.84 ADAMTS5 (0.43) MEN1NPC1ALDH1A1GAAMAPT
SCHEMBL7921426 0.83 PIM1 (0.40) MEN1ALDH1A1GAAMAPTKMT2A
SCHEMBL7929873 0.81 ELANE (0.38) ALDH1A1ELANECTSG
SCHEMBL7928250 0.81 ELANE (0.40) ELANEFAAHCTSG
SCHEMBL7921360 0.81 MAPK14 (0.36) ELANECTSG
SCHEMBL7930388 0.80 ELANE (0.37) MEN1KMT2AELANEFAAHCTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed