SCHEMBL7930657

SCHEMBL7930657

CCCCOc1c(F)c2c(c(F)c1Nc1ccccc1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADAMTS5 Q9UNA0 2/20 0.43
CCNE2 O96020 3/20 0.37
CCNE1 P24864 3/20 0.37
CDK2 P24941 3/20 0.37
CCNB2 O95067 1/20 0.37
CDK1 P06493 1/20 0.37
FGFR1 P11362 1/20 0.37
CDK4 P11802 1/20 0.37
CCNB1 P14635 1/20 0.37
CCNA2 P20248 1/20 0.37
FGFR2 P21802 1/20 0.37
FGFR4 P22455 1/20 0.37
FGFR3 P22607 1/20 0.37
CCND1 P24385 1/20 0.37
CCND2 P30279 1/20 0.37
CCND3 P30281 1/20 0.37
CCNA1 P78396 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
CXCR2 P25025 4/20 0.36
MEN1 O00255 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930029 0.92 ADAMTS5 (0.43) ADAMTS5CCNE2CCNE1CDK2CXCR2
SCHEMBL7933295 0.88 ADAMTS5 (0.39) ADAMTS5FAAH
SCHEMBL7930614 0.86 ADAMTS5 (0.40) ADAMTS5CXCR2L3MBTL1FAAHALDH1A1
SCHEMBL7930686 0.85 ELANE (0.38) CCNE2CCNE1CDK2CCNB2CDK1
SCHEMBL7930633 0.85 ELANE (0.38) CXCR2MEN1MAPTKMT2ANPC1
SCHEMBL7929794 0.85 PKM (0.44) ADAMTS5CXCR2MEN1MAPTKMT2A
SCHEMBL7933041 0.85 PDE4B (0.38) CXCR2
SCHEMBL7928355 0.84 ELANE (0.37) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL7929778 0.84 MAPT (0.51) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL7930671 0.84 KMT2A (0.43) CXCR2MEN1MAPTKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed