Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692247 | 0.69 | SNCA (0.45) | CES1MAPTKMT2ATRPA1SCN5A | |
| SCHEMBL7929271 | 0.69 | KDM4E (0.53) | POLBKDM4EMAPTKMT2ACA12 | |
| SCHEMBL6946306 | 0.63 | AR (0.47) | TRPA1SCN5ASCN9ADHODHPGR | |
| SCHEMBL16609826 | 0.63 | AR (0.43) | MAPTKMT2ATRPA1SCN5ASCN9A | |
| SCHEMBL23084386 | 0.61 | CES1 (0.41) | CES1POLBKDM4ERETTGM2 | |
| SCHEMBL23831366 | 0.60 | SCN5A (0.41) | MAPTKMT2ATRPA1SCN5ASCN9A | |
| SCHEMBL28083895 | 0.60 | AR (0.46) | CES1POLBTRPA1SCN5ASCN9A | |
| SCHEMBL2264074 | 0.59 | CES1 (0.51) | CES1TGM2PGR | |
| SCHEMBL901107 | 0.58 | GPR3 (0.46) | CES1TRPA1SCN5AKIF11GPR3 | |
| SCHEMBL28364202 | 0.58 | TRPV4 (0.48) | CES1TRPA1SCN5ASCN9APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | claimed |
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | disclosed |