SCHEMBL7930873

SCHEMBL7930873

O=C1c2ccc(Nc3ccccc3)cc2C(=O)c2c(O)ccc(O)c21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.56
KMT2A Q03164 8/20 0.56
MAPT P10636 7/20 0.56
MAOA P21397 5/20 0.56
TDP1 Q9NUW8 4/20 0.50
MAPK1 P28482 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
APP P05067 1/20 0.50
LMNA P02545 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TSHR P16473 2/20 0.49
CYP1A2 P05177 1/20 0.49
MAPK14 Q16539 1/20 0.48
TNNI3 P19429 1/20 0.48
TNNT2 P45379 1/20 0.48
TNNC1 P63316 1/20 0.48
HKDC1 Q2TB90 1/20 0.48
HPGD P15428 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9543511 0.83 APP (0.59) MEN1KMT2AMAPTMAOATDP1
SCHEMBL7928282 0.82 APP (0.56) MEN1KMT2AMAPTMAOATDP1
SCHEMBL7921412 0.82 TOP2A (0.45) MEN1KMT2AMAPTMAOATDP1
SCHEMBL7928231 0.82 MEN1 (0.53) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL7921190 0.82 P2RX1 (0.46) MEN1KMT2AMAPTMAOAALDH1A1
SCHEMBL14675727 0.81 APP (0.57) MEN1KMT2AMAPTMAOATDP1
SCHEMBL7930693 0.81 CASP6 (0.48) MEN1KMT2AMAPTMAOAL3MBTL1
SCHEMBL7928287 0.81 P2RY2 (0.48) MEN1KMT2AMAPTMAPK1NPC1
SCHEMBL7933233 0.79 DHODH (0.47) MEN1KMT2AMAPTMAOATDP1
SCHEMBL7929799 0.79 MEN1 (0.46) MEN1KMT2AMAPTMAOATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed