SCHEMBL7928282

SCHEMBL7928282

COc1ccc(Nc2ccc3c(c2)C(=O)c2c(O)ccc(O)c2C3=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.56
MAPT P10636 7/20 0.49
KDM4E B2RXH2 3/20 0.49
MAPK1 P28482 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
RAB9A P51151 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
GAA P10253 3/20 0.49
THRB P10828 2/20 0.49
NPC1 O15118 2/20 0.49
RECQL P46063 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
POLB P06746 3/20 0.48
ALDH1A1 P00352 2/20 0.48
NSD2 O96028 1/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MEN1 O00255 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928231 0.88 MEN1 (0.53) MAPTMAPK1RAB9ATDP1GAA
SCHEMBL29120743 0.83 APP (0.67) APPMAPTKDM4EMAPK1L3MBTL1
SCHEMBL7930873 0.82 MEN1 (0.56) APPMAPTKDM4EMAPK1L3MBTL1
SCHEMBL10658788 0.81 MAPT (0.63) MAPTKDM4EMAPK1L3MBTL1RAB9A
SCHEMBL7927191 0.79 EGFR (0.51) MAPTKDM4EMAPK1L3MBTL1RAB9A
SCHEMBL11416802 0.78 MAPT (0.50) MAPTKDM4EMAPK1L3MBTL1RAB9A
SCHEMBL7921412 0.77 TOP2A (0.45) APPMAPTKDM4EMAPK1L3MBTL1
SCHEMBL7933144 0.77 HPGD (0.53) MAPTKDM4ERAB9ATHRBRECQL
SCHEMBL7930693 0.76 CASP6 (0.48) MAPTL3MBTL1POLBHPGDSMN1; SMN2
SCHEMBL7928395 0.76 HPGD (0.51) MAPTKDM4EMAPK1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed