Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931865 | 0.82 | ABCC8 (0.41) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL4266841 | 0.81 | KDM4E (0.56) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL7929271 | 0.79 | KDM4E (0.53) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL7931902 | 0.78 | KDM4E (0.52) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL9813147 | 0.65 | MAPT (0.63) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL9813220 | 0.64 | KMT2A (0.58) | KDM4EMAPTKMT2APOLBCA12 | |
| Water SCHEMBL7951330 | 0.63 | KDM4E (0.44) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL9829945 | 0.62 | KDM4E (0.56) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL8878883 | 0.62 | MAPT (0.72) | KDM4EMAPTKMT2APOLBCA12 | |
| SCHEMBL7944400 | 0.62 | KDM4E (0.45) | KDM4EMAPTKMT2APOLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | claimed |
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | disclosed |