Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597786 | 0.84 | AKR1C3 (0.55) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL29683548 | 0.84 | AKR1C3 (0.55) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL570739 | 0.83 | AKR1C3 (0.55) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL8495472 | 0.82 | MAPT (0.51) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL31502529 | 0.82 | AKR1C3 (0.53) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL9295747 | 0.81 | AKR1C3 (0.61) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL1129191 | 0.78 | PRNP (0.59) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL30549381 | 0.77 | MAPT (0.54) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL723657 | 0.77 | AKR1C3 (0.61) | ALDH1A1AKR1C3MAPTPOLBMEN1 | |
| SCHEMBL29913321 | 0.77 | AKR1C3 (0.61) | ALDH1A1AKR1C3MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095005-A1 | PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES | ALBEMARLE CORPORATION (US) | 2001-05-02 | — | — | EP | disclosed |
| US-6096920-A | LARGE-SCALE PRODUCTION OF CERTAIN AROMATICALLY-SUBSTITUTED ALIPHATIC CARBOXYLIC ACIDS AND THEIR ACID DERIVATIVES | ALBEMARLE CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| WO-2000002840-A1 | PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES | ALBEMARLE CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-1999038833-A1 | PROCESS FOR THE HALOGENATION OF ALDEHYDES AND KETONES | BROMINE COMPOUNDS LTD. (IL) | 1999-08-05 | — | — | WO | disclosed |
| US-5750631-A | CURABLE EPOXIDIZED PHENOLIC RESIN CONTAINING CHLORINE AND/OR BROMINE; FIREPROOFING, BY-PRODUCT INHIBITION | SHELL OIL COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| EP-0293115-B1 | Melt-stable poly(arylene thiotherketone) and production process thereof | KUREHA CHEMICAL IND CO LTD (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5378772-A | Copolymerization of poly(arylene thioetherketoneketones) | KUREHA KAGAKU KOGYO K.K. (JP) | 1995-01-03 | — | — | US | disclosed |
| US-5378771-A | Sulfiding dihalobenzene and bis(halobenzoyl)benzene in two steps to copolymerize poly(arylene thioetherketoneketones) | KUREHA KAGAKU KOGYO K.K.K. (JP) | 1995-01-03 | — | — | US | disclosed |
| US-5248743-A | Polythioethers | KUREHA KAGAKU KOGYO K.K. (JP) | 1993-09-28 | — | — | US | disclosed |
| US-5153279-A | Heat resistance, melt processability | KUREHA KAGAKU KOGYO K.K. (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5153264-A | Heating dihalo aromatic compound and alkali metal sulfide, mixing with dihalo aromatic carbonyl compound; organic amide and water solvent | KUREHA KAGAKU KOGYO K.K. (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5153278-A | Heat resistance, workability; materials handling; molding materials; films | KUREHA KAGAKU KOGYO K.K. (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5120808-A | Melt processability, heat resistance polyether ketone polymers | KUREHA KAGAKU KOGYO K.K. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0435674-A2 | High-heat-resistant, crystalline block copolymers and production process thereof | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0369620-A2 | Poly(arylene thioether)block copolymer and production process thereof | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4895925-A | HEAT RESISTANT MOLDING MATERIAL | KUREHA KAGAKU KOGYO K.K. (JP) | 1990-01-23 | — | — | US | disclosed |
| US-4886871-A | REACTING ALKALI METAL SULFIDE AND DIHALOGENATED COMPOUNDS | KUREHA KAGAKU KOGYO K. K. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0293115-A2 | Melt-stable poly(arylene thiotherketone) and production process thereof | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-30 | — | — | EP | disclosed |