Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928491 | 0.90 | ALDH1A1 (0.42) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL6457663 | 0.86 | L3MBTL1 (0.46) | L3MBTL1MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL7723145 | 0.82 | MAPT (0.47) | MAPTALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL27558621 | 0.82 | L3MBTL1 (0.46) | L3MBTL1MAPTCYP3A4TSHRATM | |
| SCHEMBL284444 | 0.81 | CYP3A4 (0.56) | L3MBTL1CYP3A4TSHRATMTDP1 | |
| SCHEMBL3005960 | 0.81 | CYP3A4 (0.40) | L3MBTL1CYP3A4TSHRATMTDP1 | |
| SCHEMBL77808 | 0.79 | CYP3A4 (0.42) | L3MBTL1CYP3A4TSHRATMTDP1 | |
| SCHEMBL17627924 | 0.78 | ALDH1A1 (0.46) | L3MBTL1CYP3A4TSHRATMTDP1 | |
| SCHEMBL284594 | 0.77 | CYP3A4 (0.51) | L3MBTL1CYP3A4TSHRATMTDP1 | |
| SCHEMBL4887850 | 0.76 | CYP3A4 (0.39) | L3MBTL1CYP3A4TSHRATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112312-A1 | POLYMER COMPOUND WITH IMPROVED GLOSS PROPERTIES | Ciba SC Holding AG (CH) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015708-A1 | POLYMER COMPOUND WITH IMPROVED GLOSS PROPERTIES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-23 | — | — | WO | disclosed |
| EP-0729946-B1 | Condensates of butyne-linked hindered amines | CIBA SC HOLDING AG (CH) | 1999-12-15 | — | — | EP | disclosed |