SCHEMBL6928491

SCHEMBL6928491

CCCCC(CC)COC(=O)CCc1cc(-c2nc3cc(Cl)ccc3s2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
SENP7 Q9BQF6 2/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CYP3A4 P08684 2/20 0.37
TSHR P16473 1/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PPARA Q07869 6/20 0.36
AGPAT2 O15120 4/20 0.36
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
HDAC6 Q9UBN7 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931248 0.90 L3MBTL1 (0.42) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL6050509 0.87 SENP7 (0.44) SENP7CASP3SENP8SENP6PPARA
SCHEMBL17627924 0.83 ALDH1A1 (0.46) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL7642933 0.83 AGPAT2 (0.47) SENP7CASP3SENP8SENP6CYP3A4
SCHEMBL6928494 0.83 SENP7 (0.37) ALDH1A1MAPK1SENP7CASP3SENP8
SCHEMBL990405 0.80 ALDH1A1 (0.42) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL29496845 0.79 ALDH1A1 (0.43) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL76644 0.79 ALDH1A1 (0.43) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL284444 0.79 CYP3A4 (0.56) ALDH1A1MAPK1CYP3A4TSHRATM
SCHEMBL7647071 0.77 ALDH1A1 (0.40) ALDH1A1MAPK1CYP3A4TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465943-A2 FLAME RETARDANT CONPOSITIONS Ciba SC Holding AG (CH) 2004-10-13 EP disclosed
WO-2003050175-A2 FLAME RETARDANT CONPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-06-19 WO disclosed
EP-1232209-A1 DIMERIC LIGHT STABILIZERS FOR POLYOLEFINS AND POLYOLEFIN COPOLYMERS Ciba SC Holding AG (CH) 2002-08-21 EP disclosed
WO-2001040367-A1 DIMERIC LIGHT STABILIZERS FOR POLYOLEFINS AND POLYOLEFIN COPOLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-06-07 WO disclosed
WO-1998054174-A1 BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-12-03 WO disclosed