SCHEMBL7931366

SCHEMBL7931366

CCOC(=O)CCCn1cc(C(=O)c2ccc(NCc3ccc(CC)cc3)c(OC(Cl)CC)c2)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.49
SRD5A1 P18405 4/20 0.43
SRD5A2 P31213 4/20 0.43
CREBBP Q92793 1/20 0.43
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CNR2 P34972 4/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933927 0.86 CNR1 (0.55) CNR1SRD5A1SRD5A2CREBBPPOLB
Hydrochloric Acid SCHEMBL7924603 0.78 ADRA1D (0.46) CNR1
SCHEMBL8793533 0.76 SRD5A1 (0.64) CNR1SRD5A1SRD5A2CREBBPPOLB
SCHEMBL7931372 0.76 CNR1 (0.53) CNR1CREBBPCNR2LMNA
SCHEMBL7931370 0.75 CNR1 (0.51) CNR1SRD5A1SRD5A2CREBBPPOLB
SCHEMBL7861333 0.74 CNR1 (0.67) CNR1SRD5A1SRD5A2CREBBPPOLB
SCHEMBL9337423 0.74 SRD5A1 (0.59) CNR1SRD5A1SRD5A2CREBBPPOLB
SCHEMBL9267345 0.74 CNR1 (0.57) CNR1SRD5A1SRD5A2CREBBPPOLB
SCHEMBL8792140 0.73 CNR1 (0.66) CNR1SRD5A1SRD5A2CREBBPPOLB
SCHEMBL7933951 0.73 CNR1 (0.54) CNR1SRD5A1SRD5A2CREBBPPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242449-B1 TREATING PROSTATIC HYPERTROPHY, URINATION DISORDERS ASSOCIATED WITH PROSTATIC HYPERTROPHY, MALE PATTERN ALOPECIA, OR ACNE ZERIA PHARMACEUTICAL CO., LTD. (JP) 2001-06-05 US disclosed
EP-0997457-A1 3-BENZOYLINDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-05-03 EP disclosed