Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931370 | 0.78 | CNR1 (0.51) | CNR1CREBBPCNR2 | |
| SCHEMBL7933927 | 0.77 | CNR1 (0.55) | CNR1CREBBPCNR2LMNA | |
| SCHEMBL8793533 | 0.76 | SRD5A1 (0.64) | CNR1CREBBPCNR2LMNAMAPT | |
| SCHEMBL7924583 | 0.76 | CNR1 (0.58) | CNR1CREBBPCNR2 | |
| SCHEMBL7931366 | 0.76 | CNR1 (0.49) | CNR1CREBBPCNR2LMNA | |
| SCHEMBL7860934 | 0.75 | CNR1 (0.53) | CNR1CREBBPCNR2MAPTSMN1; SMN2 | |
| SCHEMBL9337423 | 0.74 | SRD5A1 (0.59) | CNR1CREBBPCNR2LMNASMN1; SMN2 | |
| SCHEMBL9337553 | 0.72 | SRD5A1 (0.57) | CNR1CREBBPCNR2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7924603 | 0.72 | ADRA1D (0.46) | CNR1 | |
| SCHEMBL8792140 | 0.72 | CNR1 (0.66) | CNR1CREBBPCNR2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242449-B1 | TREATING PROSTATIC HYPERTROPHY, URINATION DISORDERS ASSOCIATED WITH PROSTATIC HYPERTROPHY, MALE PATTERN ALOPECIA, OR ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0997457-A1 | 3-BENZOYLINDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |