Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879902 | 0.86 | APEX1 (0.38) | APEX1NOTUM | |
| SCHEMBL2954135 | 0.76 | SOS1 (0.32) | NOTUM | |
| SCHEMBL7876486 | 0.73 | NOTUM (0.36) | GLAPOLBGAATSHRNOTUM | |
| SCHEMBL29702046 | 0.73 | NOTUM (0.36) | GLAPOLBGAATSHRNOTUM | |
| SCHEMBL2965251 | 0.73 | NOTUM (0.41) | GLAPOLBGAATSHRNOTUM | |
| SCHEMBL5667400 | 0.71 | CES2 (0.36) | APEX1NOTUM | |
| SCHEMBL15286499 | 0.71 | EPAS1 (0.36) | APEX1GAANOTUM | |
| SCHEMBL23388111 | 0.71 | ASPH (0.42) | NOTUM | |
| SCHEMBL4922062 | 0.70 | GPR35 (0.33) | — | |
| SCHEMBL29679053 | 0.70 | GAA (0.45) | APEX1GLAPOLBGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255545-B1 | BROMINATION OF BENZENE, M-BIS/TRIFLUOROMETHYL/-WITH 1,3-DIBROMO-5,5-DIMETHYLHYDANTOIN OR BROMOSUCCINIMIDE IN THE PRESENCE OF ACETIC ACID AND SULFURIC ACID | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |