Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | SYK | P43405 | 2/20 | 0.74 |
| ▸ | EGFR | P00533 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | GALR2 | O43603 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | FBP1 | P09467 | 4/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | ABL2 | P42684 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727003 | 1.00 | VCP (1.00) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL807768 | 1.00 | VCP (1.00) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL28863042 | 0.98 | VCP (0.97) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL4146797 | 0.89 | VCP (0.79) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL1158756 | 0.88 | VCP (0.78) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL1158758 | 0.88 | VCP (0.78) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL2742572 | 0.88 | VCP (0.78) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL7207216 | 0.88 | VCP (0.78) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL1411603 | 0.88 | VCP (0.78) | VCPALDH1A1MAPK1SMN1; SMN2SYK | |
| SCHEMBL3100101 | 0.87 | VCP (0.77) | VCPALDH1A1MAPK1SMN1; SMN2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925293-B | Preparation method of dopamine hydrochloride | 山东达冠医药科技有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-111925293-A | Preparation method of dopamine hydrochloride | 山东达冠医药科技有限公司 | 2020-11-13 | — | — | CN | claimed |
| CN-108658778-A | A kind of new preparation process of 3,4- dimethoxys-beta-nitrostyrene | 上海华堇生物技术有限责任公司 | 2018-10-16 | — | — | CN | claimed |
| CN-108358913-A | A kind of green synthesis process of rotundine sulfate | 四川依科制药有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-101973903-A | Method for synthesizing capsaicin homolog | UNIV ZHEJIANG | 2011-02-16 | — | — | CN | claimed |
| EP-1027332-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-08-16 | — | — | EP | claimed |
| WO-1999018074-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Britol-Myers Squibb Pharma Company (US) | 1999-04-15 | — | — | WO | claimed |
| EP-4616906-A2 | BENZO[A]PHENANTHRIDINE DERIVATIVES AS YAP/TAZ INHIBITORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-09-17 | — | — | EP | disclosed |
| US-20220267277-A1 | DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2022-08-25 | — | — | US | disclosed |
| CN-111925293-B | Preparation method of dopamine hydrochloride | 山东达冠医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-111925293-B | Preparation method of dopamine hydrochloride | 山东达冠医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-4003339-A2 | DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-107188771-B | Chiral synthesis method of gamma-nitrophenol compound | 浙江工业大学 | 2021-08-24 | — | — | CN | disclosed |
| EP-0050370-B1 | SUBSTITUTED CYCLIC AMINES | USV PHARMACEUTICAL CORPORATION (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4342692-A | USEFUL AS CARDIOTONIC AGENTS, ANTIHYPERTENSIVE AGENTS, AND ANTIALL | USV PHARMACEUTICAL CORPORATION (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0050370-A1 | Substituted cyclic amines | USV PHARMACEUTICAL CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4148795-A | Dithiocarbamate ester bactericides and fungicides | AMERICAN CYANAMID COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4038288-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4011230-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-3989714-A | ANTIVIRAL | WARNER-LAMBERT COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267277-A1 | DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE | PRLHR, YAP1, MST1R | VCP 3545/4885ALDH1A1 1281/4885MAPK1 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.