Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494874 | 0.78 | MAPT (0.44) | KMT2ARAB9ANPC1MEN1POLB | |
| Nitric Acid SCHEMBL11293599 | 0.74 | MAPT (0.43) | KMT2ARAB9ANPC1MEN1POLB | |
| SCHEMBL8205651 | 0.70 | MAPT (0.46) | KMT2ARAB9ANPC1MEN1POLB | |
| Nitric Acid SCHEMBL6665150 | 0.70 | MEN1 (0.61) | KMT2ARAB9ANPC1MEN1POLB | |
| SCHEMBL28560105 | 0.69 | MAPT (0.44) | KMT2ANPC1MEN1SMN1; SMN2MAPT | |
| SCHEMBL28570620 | 0.68 | MAPT (0.46) | KMT2ARAB9ANPC1MEN1POLB | |
| SCHEMBL1635786 | 0.68 | MAPT (0.54) | KMT2ARAB9ANPC1MEN1POLB | |
| SCHEMBL29787356 | 0.67 | RAB9A (0.52) | KMT2ARAB9ANPC1MEN1POLB | |
| SCHEMBL1635805 | 0.66 | RAB9A (0.49) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL8898712 | 0.64 | ELANE (0.61) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934370-A4 | ORGANIC SOLVENT BASED INK FOR INVISIBLE MARKING/IDENTIFICATION | EASTMAN CHEM CO (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0934370-A1 | ORGANIC SOLVENT BASED INK FOR INVISIBLE MARKING/IDENTIFICATION | EASTMAN CHEMICAL COMPANY (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998018871-A1 | ORGANIC SOLVENT BASED INK FOR INVISIBLE MARKING/IDENTIFICATION | EASTMAN CHEMICAL COMPANY (US) | 1998-05-07 | — | — | WO | disclosed |
| EP-0085157-A2 | Method and apparatus for identifying indicia | International Business Machines Corporation (US) | 1983-08-10 | — | — | EP | disclosed |
| EP-0085157-A2 | Method and apparatus for identifying indicia | International Business Machines Corporation (US) | 1983-08-10 | — | — | EP | disclosed |