Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.62 |
| ▸ | RARG | P13631 | 5/20 | 0.62 |
| ▸ | RARA | P10276 | 4/20 | 0.62 |
| ▸ | RXRA | P19793 | 18/20 | 0.55 |
| ▸ | RXRB | P28702 | 10/20 | 0.55 |
| ▸ | RXRG | P48443 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922987 | 0.83 | RARA (0.43) | RARBRARGRARARXRARXRB | |
| SCHEMBL7932916 | 0.81 | RXRA (0.69) | RARBRARGRARARXRARXRB | |
| SCHEMBL3234003 | 0.79 | RARB (0.64) | RARBRARGRARARXRARXRB | |
| SCHEMBL3233993 | 0.79 | RARB (0.64) | RARBRARGRARARXRARXRB | |
| SCHEMBL7932710 | 0.77 | RARG (0.38) | RARBRARGRARARXRARXRB | |
| SCHEMBL156460 | 0.77 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL10841477 | 0.77 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| Hydrochloric Acid SCHEMBL4432609 | 0.76 | RARB (0.97) | RARBRARGRARARXRARXRB | |
| SCHEMBL7023945 | 0.72 | RARB (0.55) | RARBRARGRARARXRARXRB | |
| SCHEMBL726140 | 0.72 | RXRA (1.00) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | claimed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | claimed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |