SCHEMBL7932063

SCHEMBL7932063

Nc1nc(Cl)c(OC(F)F)c(C(F)(F)F)n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934006 0.83 DPP4 (0.31)
SCHEMBL7932049 0.77 CYP1A2 (0.32)
SCHEMBL7932055 0.72 CCNA2 (0.39)
SCHEMBL2573734 0.71 KDM4E (0.33) KDM4E
SCHEMBL8874425 0.71 NUDT1 (0.33) KDM4E
SCHEMBL8874150 0.71 LRRK2 (0.34)
SCHEMBL8874055 0.71 RAB9A (0.31)
SCHEMBL7933967 0.69 GAA (0.34)
SCHEMBL8874251 0.69 KDM4E (0.39) KDM4E
SCHEMBL23998125 0.68 KDM4E (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235904-B1 VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed
US-5283332-A 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1994-02-01 US disclosed