Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935910 | 0.87 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7806822 | 0.85 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7796331 | 0.80 | KMT2A (0.43) | HSP90AA1HSP90AB1KDM4EKMT2ACYP1A2 | |
| SCHEMBL7934010 | 0.80 | KMT2A (0.49) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL7804829 | 0.79 | NPC1 (0.44) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5891451 | 0.78 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7932041 | 0.76 | KDM4E (0.44) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL10900625 | 0.76 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL10699737 | 0.75 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2392109 | 0.75 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |