Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935910 | 0.88 | HSP90AA1 (0.35) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7808650 | 0.87 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7796331 | 0.81 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2HSP90AB1HSP90AA1 | |
| SCHEMBL9194620 | 0.81 | ATF1 (0.36) | — | |
| SCHEMBL7932060 | 0.80 | HSP90AA1 (0.50) | KMT2AALDH1A1HSP90AB1HSP90AA1KDM4E | |
| SCHEMBL7804829 | 0.80 | NPC1 (0.44) | SMN1; SMN2ALDH1A1RAB9AHSP90AB1HSP90AA1 | |
| SCHEMBL8874243 | 0.76 | RAB9A (0.48) | SMN1; SMN2ALDH1A1RAB9AHSP90AB1HSP90AA1 | |
| SCHEMBL8874417 | 0.76 | GABRP (0.32) | KMT2AMEN1HSP90AB1HSP90AA1MAPT | |
| SCHEMBL8874050 | 0.76 | NUDT1 (0.44) | KMT2AMEN1SMN1; SMN2HSP90AB1HSP90AA1 | |
| SCHEMBL8874141 | 0.76 | NUDT1 (0.51) | HSP90AB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | claimed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | claimed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | claimed |
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |